identify survival predictors of the first kidney transplantation: a retrospective cohort study.

the first kidney transplant survival is very important. we know that short-term survival of kidney transplantation is improved over the past two decades in iran; however, no information is available on long-term survival and predictors. this study explored factors influencing long-term renal transplant survival at northwest of iran.in this single-center, study, survival rates and half-life of 201 the first kidney transplants between 1999 and 2008 were measured by a historical-cohort study in imam khomeini hospital in urmia, iran. the log-rank test and cox-regression model were used to compare survival curves and determine factor affecting graft survival time, respectively.first graft survival from one, five, and 10 years was 96%, 89%, and 46%, respectively. mean±se and median±se of first graft survival time was 3061±105.01 day (95% ci: 2855.47-3267.11 day) and 3411±282.1 day (95%ci: 2858.08-3963.92), respectively. predictors of first graft rejection were recipient age (p=0.001), ldl cholesterol (p=0.008), immunosuppressive drugs (p=0.047), serum creatinine three and six months (p=0.042 and 0.001, respectively) and related donor family (p=0.037).patients with first graft transplantation had a moderate long-term survival. the study showed that small age at transplant, low ldl cholesterol before transplant, and relative to donor, could be decrease the risk graft loss.